Floodplain (126)

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Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fresh full-thickness human skin explants, a model containing all skin cell types. Results show that skin explants have significant capacity ...

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Tissue function depends on hierarchical structures extending from single cells (B10 lm) to functional subunits (100 lm– 1 mm) that coordinate organ functions. Conventional cell culture disperses tissues into single cells while neglecting higher-order processes. The application of semiconductordriven microtechnology in the biomedical arena now allows fabrication of microscale tissue subunits tha...

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Carboxylesterase 1 (CES1) is the major hydrolase in human liver. The enzyme is involved in the metabolism of several important therapeutic agents, drugs of abuse, and endogenous compounds. However, no studies have described the role of human CES1 in the activation of two commonly prescribed angiotensinconverting enzyme inhibitors: enalapril and ramipril. Here, we studied recombinant human CES1a...

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Previous Volumes 1 - 126

Volume 126 Published by Foundation of Computer Science (FCS), NY, USA Indexed with Google Scholar, CiteSeer and CSA Technology Research Database, ProQuest Volume 125 Published by Foundation of Computer Science (FCS), NY, USA Indexed with Google Scholar, CiteSeer and CSA Technology Research Database, ProQuest Volume 124 Published by Foundation of Computer Science (FCS), NY, USA Indexed with Go...

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126 - 128 Ponnudurai G.pmd

The occurrence of caecal nematode, Subulura brumpti has become more common in quails being maintained in commercial farms in Tamil Nadu, India. Two trials were carried out to study the biology and pathology of S. brumpti in quails. In the first trial, eight grower quails were divided into two groups (T1 and T2) comprising of four birds each. The birds belonged to the group T1 was infected with ...

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ژورنال

عنوان ژورنال: Refract: An Open Access Visual Studies Journal

سال: 2020

ISSN: 2640-9429

DOI: 10.5070/r73151225